ABSTRACT
Background: Inguinal hernia is one of the most common surgical conditions operated by the surgeon. The purpose of the study paper was to provide diagnostic and therapeutic resources to deal with certain difficult situations in hernia repair.Methods: A retrospective analysis of 8 rare and atypical inguinal hernias was conducted for a period of 2 years at NRI General Hospital, which includes cases like Loss of domain hernias and hernias with atypical contents; which stood as diagnostic and management challenge to the surgeon.Results: Of the eight very rare and atypical cases operated, no postoperative complications were noted except one which developed a scrotal abscess after one month of discharge.Conclusions: The infrequent encounter with rare and atypical hernias stands a diagnostic challenge to the surgeon. Inguinal hernia repair even-though looks simple yet may sometimes be very difficult.
ABSTRACT
In vivo effect of lead on Na, K(+)-ATPase was studied in plasma membrane/mitochondrial fraction of P. indicus post-larvae (PL), exposed to 30 days to a sublethal concentration (1.44 ppm) of lead. A significant (P < 0.05) decrease in the enzyme activity was observed for exposed PL with respect to their controls at different intervals except 24hr. Further the substrate (ATP) and ion (Na+ and K+)-dependent kinetics of Na+, K(+)-ATPase was studied with the plasma membrane/mitochondrial fractions of control and 30 days exposed PL. The apparent KM and V(max). values were calculated to determine the nature of inhibition. Both the control and exposed PL showed almost the same apparent KM values in the presence of different substrate or ion concentrations indicating that lead interacts with the enzyme at a different binding site.